Manchester City vs Arsenal

The title race takes centre stage at the Etihad as two of the league's most tactically sophisticated managers go head-to-head. Pep Guardiola's side will look to control possession through their midfield diamond, while Mikel Arteta has set up Arsenal to be devastating on the counter-attack.

Key battle: Rodri vs Martin Odegaard. If City can nullify Odegaard's creativity in the half-spaces, Arsenal's attacking output drops significantly.

Liverpool vs Tottenham

Anfield has been a fortress for Liverpool this season. Tottenham will need to be disciplined defensively and clinical on the break to leave with anything.

Watch for Salah cutting inside onto his left foot against Tottenham's inverted full-back setup.